期刊名：International Journal of Translational Medicine （国际转化医学期刊）

期刊主页：https://www.mdpi.com/journal/ijtm

导语：

本期编辑荐读精选2024-2025年发表于IJTM期刊的高被引论文，聚集转化医学领域癌症治疗，药物与靶点，氧化应激，生物标志物等多个研究方向。期望为相关领域学者提供有价值的研究参考与学术启发，欢迎关注与阅读。

1. Advancements Exploring Major Depressive Disorder: Insights on Oxidative Stress, Serotonin Metabolism, BDNF, HPA Axis Dysfunction, and Pharmacotherapy Advances

重度抑郁障碍研究进展：氧化应激、血清素代谢、脑源性神经营养因子、HPA轴功能障碍及药物治疗探析

文章链接： https://www.mdpi.com/2673-8937/4/1/10

MDPI and ACS 引用格式： Correia, A.S.; Vale, N. Advancements Exploring Major Depressive Disorder: Insights on Oxidative Stress, Serotonin Metabolism, BDNF, HPA Axis Dysfunction, and Pharmacotherapy Advances. Int. J. Transl. Med. 2024, 4, 176–196. https://doi.org/10.3390/ijtm4010010

2. Recent Advances in Marine-Derived Bioactives Towards Cancer Therapy

海洋来源生物活性物质在癌症治疗领域的最新进展

文章链接：https://www.mdpi.com/2673-8937/4/4/51

MDPI and ACS 引用格式：

Tamzi, N.N.; Rahman, M.M.; Das, S. Recent Advances in Marine-Derived Bioactives Towards Cancer Therapy. Int. J. Transl. Med. 2024, 4, 740–781. https://doi.org/10.3390/ijtm4040051

3. Potential of Exosomes as Therapeutics and Therapy Targets in Cancer Patients

外泌体作为癌症患者治疗药物与治疗靶点的潜力

文章链接：https://www.mdpi.com/2673-8937/4/2/15

MDPI and ACS 引用格式：

Schwarzenbach, H. Potential of Exosomes as Therapeutics and Therapy Targets in Cancer Patients. Int. J. Transl. Med. 2024, 4, 247–261. https://doi.org/10.3390/ijtm4020015

4. Human Sputum Proteomics: Advancing Non-Invasive Diagnosis of Respiratory Diseases with Enhanced Biomarker Analysis Methods

人类痰液蛋白质组学：通过增强的生物标志物分析方法推动呼吸系统疾病的无创诊断

文章链接：https://www.mdpi.com/2673-8937/4/2/20

MDPI and ACS 引用格式：

Guzman, N.A.; Guzman, A. Human Sputum Proteomics: Advancing Non-Invasive Diagnosis of Respiratory Diseases with Enhanced Biomarker Analysis Methods. Int. J. Transl. Med. 2024, 4, 309–333. https://doi.org/10.3390/ijtm4020020

5. Emerging Strategies to Overcome Chemoresistance: Structural Insights and Therapeutic Targeting of Multidrug Resistance-Linked ATP-Binding Cassette Transporters

克服化疗耐药性的新兴策略：多药耐药相关ATP结合盒转运蛋白的结构解析与靶向治疗

文章链接： https://www.mdpi.com/2673-8937/5/1/6

MDPI and ACS 引用格式：

Nagampalli, R.S.K.; Vadla, G.P.; Nadendla, E.K. Emerging Strategies to Overcome Chemoresistance: Structural Insights and Therapeutic Targeting of Multidrug Resistance-Linked ATP-Binding Cassette Transporters. Int. J. Transl. Med. 2025, 5, 6. https://doi.org/10.3390/ijtm5010006

6. 靶向肿瘤干细胞的放射免疫治疗：以卵巢癌干性相关生物标志物 L1CAM 为例

Targeting Cancer Stem Cells with Radioimmunotherapy: The Case of the Ovarian Cancer Stemness-Associated Biomarker L1CAM

文章链接：https://www.mdpi.com/2673-8937/4/3/31

MDPI and ACS 引用格式：

Todorov, T.Z.; Schibli, R.; Béhé, M.; Grünberg, J. Targeting Cancer Stem Cells with Radioimmunotherapy: The Case of the Ovarian Cancer Stemness-Associated Biomarker L1CAM. Int. J. Transl. Med. 2024, 4, 463–485. https://doi.org/10.3390/ijtm4030031

7. NF-κB诱导激酶（NIK）在癌症治疗中的药物靶点潜力

The Druggable Target Potential of NF-κB-Inducing Kinase (NIK) in Cancer

文章链接：https://www.mdpi.com/2673-8937/5/1/1

MDPI and ACS 引用格式：

Wang, Y.; Rui, L. The Druggable Target Potential of NF-κB-Inducing Kinase (NIK) in Cancer. Int. J. Transl. Med. 2025, 5, 1. https://doi.org/10.3390/ijtm5010001

期刊简介：

主编：Prof. Dr. Pier Paolo Claudio, University of Mississippi Medical Center, USA

International Journal of Translational Medicine (ISSN 2673-8937) 创刊于2021年，是一本国际同行评审的开放获取期刊。该期刊旨在搭建基础研究与临床医学的桥梁，专注于发表始于临床问题、经实验研究获得解决方案、并最终能将成果应用于临床的转化型研究。其范围涵盖生物材料、生物技术、组学、分子医学、药物研发、基因治疗、肿瘤学、及各类疾病等具有临床适用性的前沿领域。目前，期刊已被Scopus、Embase、EBSCO、DOAJ、Dimensions等数据库收录。

联系期刊编辑部: ijtm@mdpi.com

进入期刊主页: https://www.mdpi.com/journal/ijtm

了解投稿指南: https://www.mdpi.com/journal/ijtm/instructions