期刊名：Genes

期刊主页：https://www.mdpi.com/journal/genes

Genes期刊2025年精选文章，为您提供最受欢迎的研究进展！

1. Genomic Rewilding of Domestic Animals: The Role of Hybridization and Selection in Wolfdog Breeds

驯养动物基因组再野化：狼犬品种中杂交与选择的作用

文章链接：http://www.mdpi.com/2073-4425/16/1/102

MDPI引用格式：Bácová, A.; Lucas Lledó, J.I.; Eliášová, K.; Neradilová, S.; Stronen, A.V.; Caniglia, R.; Galaverni, M.; Fabbri, E.; Mattucci, F.; Boyko, A.; et al. Genomic Rewilding of Domestic Animals: The Role of Hybridization and Selection in Wolfdog Breeds. Genes 2025, 16, 102.

2. Arabidopsis thaliana DNA Damage Response Mutants Challenged with Genotoxic Agents—A Different Experimental Approach to Investigate the TDP1α and TDP1β Genes

拟南芥DNA损伤响应突变体经基因毒性剂胁迫——探究TDP1α和TDP1β基因功能的新途径

文章链接：http://www.mdpi.com/2073-4425/16/1/103

MDPI引用格式：Bertoncini, A.; Pagano, P.; Macovei, A. Arabidopsis thaliana DNA Damage Response Mutants Challenged with Genotoxic Agents—A Different Experimental Approach to Investigate the TDP1α and TDP1β Genes. Genes 2025, 16, 103.

3. The Genetic Determinants of Listeria monocytogenes Resistance to Bacteriocins Produced by Lactic Acid Bacteria

单核细胞增生李斯特菌对乳酸菌细菌素抗性的遗传决定因素

文章链接：http://www.mdpi.com/2073-4425/16/1/50

MDPI引用格式：Zawiasa, A.; Olejnik-Schmidt, A. The Genetic Determinants of Listeria monocytogenes Resistance to Bacteriocins Produced by Lactic Acid Bacteria. Genes 2025, 16, 50. https://doi.org/10.3390/genes16010050

4. Hereditary Breast Cancer: Comprehensive Risk Assessment and Prevention Strategies

遗传性乳腺癌：综合风险评估与预防策略

文章链接：http://www.mdpi.com/2073-4425/16/1/82

MDPI引用格式：Manna, E.D.F.; Serrano, D.; Cazzaniga, L.; Mannucci, S.; Zanzottera, C.; Fava, F.; Aurilio, G.; Guerrieri-Gonzaga, A.; Risti, M.; Calvello, M.; et al. Hereditary Breast Cancer: Comprehensive Risk Assessment and Prevention Strategies. Genes 2025, 16, 82.

5. Hallmarks of DNA Damage Response in Germination Across Model and Crop Species

模式与作物物种萌发过程中DNA损伤响应的标志性特征

文章链接：http://www.mdpi.com/2073-4425/16/1/95

MDPI引用格式：Sincinelli, F.; Gaonkar, S.S.; Tondepu, S.A.G.; Dueñas, C.J.; Pagano, A. Hallmarks of DNA Damage Response in Germination Across Model and Crop Species. Genes 2025, 16, 95.

6. Comparative Study of Statistical Approaches and SNP Panels to Infer Distant Relationships in Forensic Genetics

法医遗传学中推断远亲关系的统计方法与SNP基因分型技术比较研究

文章链接：http://www.mdpi.com/2073-4425/16/2/114

MDPI引用格式：Tillmar, A.; Kling, D. Comparative Study of Statistical Approaches and SNP Panels to Infer Distant Relationships in Forensic Genetics. Genes 2025, 16, 114.

7. The PLA Gene Family in Tomato: Identification, Phylogeny, and Functional Characterization

番茄PLA基因家族：鉴定、系统发育与功能解析

文章链接：http://www.mdpi.com/2073-4425/16/2/130

MDPI引用格式：Li, Z.; Yao, Z.; Ruan, M.; Wang, R.; Ye, Q.; Wan, H.; Zhou, G.; Cheng, Y.; Guo, S.; Liu, C.; et al. The PLA Gene Family in Tomato: Identification, Phylogeny, and Functional Characterization. Genes 2025, 16, 130.

8. Genomic and Transcriptomic Approaches Advance the Diagnosis and Prognosis of Neurodegenerative Diseases

基因组学与转录组学方法在神经退行性疾病诊断与预后中的应用进展

文章链接：http://www.mdpi.com/2073-4425/16/2/135

MDPI引用格式：Liu, Z.; Song, S.-Y. Genomic and Transcriptomic Approaches Advance the Diagnosis and Prognosis of Neurodegenerative Diseases. Genes 2025, 16, 135.

9. Genetic Variants of SLC22A1 rs628031 and rs622342 and Glycemic Control in T2DM Patients from Northern Mexico

墨西哥北部2型糖尿病患者SLC22A1基因rs628031与rs622342遗传变异与血糖控制的相关性研究

文章链接：http://www.mdpi.com/2073-4425/16/2/139

MDPI引用格式：Moreno-González, J.G.; Reza-López, S.A.; González-Rodríguez, E.; Siqueiros-Cendón, T.S.; Escareño Contreras, A.; Rascón-Cruz, Q.; Leal-Berumen, I. Genetic Variants of SLC22A1 rs628031 and rs622342 and Glycemic Control in T2DM Patients from Northern Mexico. Genes 2025, 16, 139.

10. Genome-Wide Runs of Homozygosity Reveal Inbreeding Levels and Trait-Associated Candidate Genes in Diverse Sheep Breeds

全基因组纯合性片段分析揭示不同绵羊品种的近交水平及性状关联候选基因

文章链接：http://www.mdpi.com/2073-4425/16/3/316

MDPI引用格式：Ma, R.; Liu, J.; Ma, X.; Yang, J. Genome-Wide Runs of Homozygosity Reveal Inbreeding Levels and Trait-Associated Candidate Genes in Diverse Sheep Breeds. Genes 2025, 16, 316.

11. The rs1360780 Variant of FKBP5: Genetic Variation, Epigenetic Regulation, and Behavioral Phenotypes

FKBP5基因rs1360780变异位点：遗传变异、表观遗传调控与行为表型

文章链接：http://www.mdpi.com/2073-4425/16/3/325

MDPI引用格式：Arancibia, M.; Manterola, M.; Ríos, U.; Moya, P.R.; Moran-Kneer, J.; Bustamante, M.L. The rs1360780 Variant of FKBP5: Genetic Variation, Epigenetic Regulation, and Behavioral Phenotypes. Genes 2025, 16, 325.

12. Evaluation of DNA in Human Teeth—Ante-Mortem and Post-Mortem Factors Affecting Degradation and Preservation: A Literature Review

人牙DNA评估——影响降解与保存的生前及死后因素：一项文献综述

文章链接：http://www.mdpi.com/2073-4425/16/4/364

MDPI引用格式：Salazar, A.M.; Huerta, P.A.; Coliboro-Dannich, V.; Castro, A.F.; Barbaro, A. Evaluation of DNA in Human Teeth—Ante-Mortem and Post-Mortem Factors Affecting Degradation and Preservation: A Literature Review. Genes 2025, 16, 364.

13. Techniques for Validating CRISPR Changes Using RNA-Sequencing Data

利用RNA测序数据验证CRISPR编辑效果的技术方法

文章链接：http://www.mdpi.com/2073-4425/16/4/369

MDPI引用格式：Rathe, S.K.; Marko, T.A.; Edwards, E.N.; Ridder, P.H.; Varshney, J.; Williams, K.B.; Johnson, J.E.; Moriarity, B.S.; Largaespada, D.A. Techniques for Validating CRISPR Changes Using RNA-Sequencing Data. Genes 2025, 16, 369.

14. Pharmacogenomic and Pharmacomicrobiomic Aspects of Drugs of Abuse

成瘾性药物的药物基因组学与药物微生物组学研究

文章链接：http://www.mdpi.com/2073-4425/16/4/403

MDPI引用格式：Borrego-Ruiz, A.; Borrego, J.J. Pharmacogenomic and Pharmacomicrobiomic Aspects of Drugs of Abuse. Genes 2025, 16, 403.

15. MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications—A Review

MTHFR基因多态性：单一基因的广泛临床意义——综述

文章链接：http://www.mdpi.com/2073-4425/16/4/441

MDPI引用格式：Araszkiewicz, A.F.; Jańczak, K.; Wójcik, P.; Bia?ecki, B.; Kubiak, S.; Szczechowski, M.; Januszkiewicz-Lewandowska, D. MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications—A Review. Genes 2025, 16, 441.

16. Role of MicroRNAs in Acute Myeloid Leukemia

MicroRNAs在急性髓系白血病中的作用机制

文章链接：http://www.mdpi.com/2073-4425/16/4/446

MDPI引用格式：Wi?nik, A.; Jarych, D.; Krawiec, K.; Strza?ka, P.; Potocka, N.; Czemerska, M.; Sa?agacka-Kubiak, A.; Pluta, A.; Wierzbowska, A.; Zawlik, I. Role of MicroRNAs in Acute Myeloid Leukemia. Genes 2025, 16, 446.

17. Autism Spectrum Disorder: Genetic Mechanisms and Inheritance Patterns

孤独症谱系障碍的遗传机制与遗传模式

文章链接：http://www.mdpi.com/2073-4425/16/5/478

MDPI引用格式：La Monica, I.; Di Iorio, M.R.; Sica, A.; Rufino, F.; Sotira, C.; Pastore, L.; Lombardo, B. Autism Spectrum Disorder: Genetic Mechanisms and Inheritance Patterns. Genes 2025, 16, 478.

18. Hypermobile Ehlers–Danlos Syndrome: Diagnostic Challenges and the Role of Genetic Testing

过度活动型埃勒斯-当洛斯综合征：诊断挑战与遗传检测的作用

文章链接：http://www.mdpi.com/2073-4425/16/5/530

MDPI引用格式：Forghani, I.; See, J.; McGonigle, W.C. Hypermobile Ehlers–Danlos Syndrome: Diagnostic Challenges and the Role of Genetic Testing. Genes 2025, 16, 530.

19. Genetic Background and Gene Essentiality

遗传背景与基因必需性研究

文章链接：http://www.mdpi.com/2073-4425/16/5/570

MDPI引用格式：G?sienica, P.; Toch, K.; Zaj?c-Garlacz, K.S.; Labocha-Derkowska, M. Genetic Background and Gene Essentiality. Genes 2025, 16, 570.

20. Epigenetic Clocks and Their Prospective Application in the Complex Landscape of Aging and Alzheimer’s Disease

表观遗传时钟及其在衰老与阿尔茨海默病复杂进程中的前瞻性应用

文章链接：http://www.mdpi.com/2073-4425/16/6/679

MDPI引用格式：Cerantonio, A.; Greco, B.M.; Citrigno, L.; De Benedittis, S.; Qualtieri, A.; Maletta, R.; Montesanto, A.; Passarino, G.; Spadafora, P.; Cavalcanti, F. Epigenetic Clocks and Their Prospective Application in the Complex Landscape of Aging and Alzheimer’s Disease. Genes 2025, 16, 679.

21. Gene-by-Environment Interactions Involving Maternal Exposures with Orofacial Cleft Risk in Filipinos

母亲环境暴露与唇腭裂风险的基因-环境交互作用：一项基于菲律宾人群的研究

文章链接：http://www.mdpi.com/2073-4425/16/8/876

MDPI引用格式：Erdogan-Yildirim, Z.; Carlson, J.C.; Mukhopadhyay, N.; Leslie-Clarkson, E.J.; Padilla, C.D.; Murray, J.C.; Beaty, T.H.; Weinberg, S.M.; Marazita, M.L.; Shaffer, J.R. Gene-by-Environment Interactions Involving Maternal Exposures with Orofacial Cleft Risk in Filipinos. Genes 2025, 16, 876.

22. Optical Genome Mapping: A New Tool for Cytogenomic Analysis

光学基因组图谱技术：细胞基因组分析的新工具

文章链接：http://www.mdpi.com/2073-4425/16/8/924

MDPI引用格式：Levy, B.; Burnside, R.D.; Akkari, Y. Optical Genome Mapping: A New Tool for Cytogenomic Analysis. Genes 2025, 16, 924.

23. Endogenous Retroviruses in Host-Virus Coevolution: From Genomic Domestication to Functional Innovation

内源性逆转录病毒在宿主-病毒协同进化中的作用：从基因组驯化到功能创新

文章链接：http://www.mdpi.com/2073-4425/16/8/964

MDPI引用格式：Jiang, R.; Zhou, J.; Liu, Y.; Zhou, G.; Fan, D.; Xiang, L.; Chen, Y.; Shao, J. Endogenous Retroviruses in Host-Virus Coevolution: From Genomic Domestication to Functional Innovation. Genes 2025, 16, 964.

Genes期刊介绍

主编：Selvarangan Ponnazhagan, The University of Alabama at Birmingham, USA

期刊主题涵盖了与DNA、RNA、染色体、基因、遗传学和多组学相关的所有内容。下设18个专题，从人类、动物、植物、微生物、分子遗传、种群进化和高新技术等多个角度全方位审视遗传学和基因组学的前沿研究。

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