近日，华南理工大学边黎明团队报道了超扩散和超渗透凝聚体在水合和脂质基质上具有很强的水下附着力。2026年3月30日，《自然-化学》杂志发表了这一成果。

开发能够在水下对多种基底（尤其是高水合性和脂质性基底）实现强效粘附的粘合剂仍是一项重大挑战。

受海洋生物中藤壶强韧粘附的启发，研究组报道了一种抗稀释且具有超铺展性的凝聚层，通过实现界面渗透与缠结，介导强效的水下粘附。将末端丁基共轭连接到聚丙二醇上，可触发水溶液的液-液相分离，并在氢键和疏水相互作用的驱动下形成PPG凝聚层。这种简单的凝聚层表现出独特的超铺展特性，能够促进在高水合性和脂质性基底上的界面润湿、渗透以及缠结界面的形成，同时富集负载的亲水性固化剂，通过快速原位光固化形成强效的水下粘合剂。

这种基于凝聚层的粘合剂在复杂水环境中对多种基底（包括具有多尺度孔隙的高水合性和脂质性基底）均表现出强效的水下粘附。通过强粘附介导的水凝胶和/或有机凝胶组装，以及对水下泄漏和组织穿孔的有效密封，验证了该粘合剂的潜在应用价值。

附：英文原文

Title: Superspreading and ultra-infiltrative coacervate mediates strong underwater adhesion on hydrated and lipidic substrates

Author: Yi, Bo, Li, Hao, Chen, Sirong, Lian, Honghui, Tan, Fengming, Yao, Haiyang, Xu, Xiayi, Zhang, Kunyu, Zhao, Pengchao, Bian, Liming

Issue&Volume: 2026-03-30

Abstract: Developing adhesives with robust underwater adhesion to diverse substrates, particularly highly hydrated and lipidic substrates, remains a major challenge. Inspired by the tough adhesion of barnacles on marine creatures, here we report a dilution-resistant and superspreading coacervate to mediate robust underwater adhesion by enabling interfacial infiltration and intertwining. Conjugation of terminal butyl groups to poly(propylene glycol) (PPG) triggers liquid–liquid phase separation of the aqueous solution and formation of PPG coacervate driven by the hydrogen bonding and hydrophobic interactions. The simple coacervate shows distinctive superspreading properties to facilitate interfacial wetting, infiltration and formation of intertwined interfaces on both the hydrated and lipidic substrates and concentrates the loaded hydrophilic curing agents to form a robust underwater adhesive by rapid in situ photocuring. The coacervate-based adhesive demonstrates strong underwater adhesion to diverse substrates, including highly hydrated and lipidic substrates with multiscale porosity and in complex aqueous environments. Potential applications of this adhesive are validated by robust adhesion-mediated hydrogel and/or organogel assemblies and effective sealing of underwater leakages and tissue perforations.

DOI: 10.1038/s41557-026-02087-9

Source: https://www.nature.com/articles/s41557-026-02087-9