近日，中国科学技术大学陈立锋团队报道了生物质衍生的可持续双原子催化剂实现了5-羟甲基糠醛高效电化学开环为2,5-己二醇。相关论文于2026年3月3日发表在《美国化学会志》上。

在温和条件下对生物质衍生的5-羟甲基糠醛进行电化学还原开环反应，是生产高附加值化学品的一条高效且可持续的途径。然而，该工艺的有效性常因催化剂在强酸环境中活性低、稳定性差而受限。

研究组通过系统筛选，确定了生物质衍生的碳负载Cu-Zn双原子活性位点可作为将HMF电化学还原开环为2,5-己二酮的高效催化剂，实现了高达91.6%的选择性和190.7 μmol mgcat^-1 h^-1的生产率，同时法拉第效率达到90.2%。这一性能比先前报道的系统高出一个数量级，综合技术经济分析表明其具有显著的经济潜力。

结合理论研究的原位电化学表征表明，HMF的电化学还原开环反应是通过表面吸附氢经由协同质子-电子转移机制引发的。其卓越的催化性能归因于双原子催化剂中Cu和Zn活性位点之间的协同作用。该研究为将生物质衍生物高效转化为高价值化学品提供了一种有前景的电化学还原方法，并实现了生物质资源的综合利用。

附：英文原文

Title: Biomass-Derived Sustainable Dual-Atom Catalysts Enabled Highly Efficient Electrochemical Reductive Ring-Opening of 5-Hydroxymethylfurfural to 2,5-Hexanediol

Author: Zhiyong Fang, Tao Gan, Wei-Xu Dong, Yong Xu, Weiyi Wang, Weihan Li, Minsi Li, Qiu-Hong Pan, Wei Hu, Xianjun Xing, Jie Zeng, Shu-Hong Yu, Li-Feng Chen

Issue&Volume: March 3, 2026

Abstract: Electrochemical reductive ring-opening (ERR) of biomass-derived 5-hydroxymethylfurfural (HMF) under mild conditions represents an efficient and sustainable route for the production of value-added chemicals. However, the effectiveness of this process is often limited by the low catalytic activity and poor stability of catalysts in highly acidic environments. Herein, we systematically screen and identify biomass-derived carbon-supported Cu–Zn dual-atom active sites as highly efficient catalysts for the EER of HMF to 2,5-hexanediol (HD), achieving a high selectivity of 91.6% and a productivity of 190.7 μmol mgcat–1 h–1, alongside an impressive Faradaic efficiency of 90.2%. This performance surpasses that of previously reported systems by an order of magnitude, highlighting its significant economic potential, as evidenced by comprehensive technoeconomic analysis. In situ electrochemical characterizations, combined with theoretical studies, suggest that the ERR of HMF is induced by surface-adsorbed hydrogen through a concerted proton–electron transfer mechanism. The outstanding catalytic performance is attributed to the synergistic interaction between Cu and Zn active sites in the dual-atom catalyst. This study provides a promising electrochemical reductive approach for the efficient conversion of biomass derivatives into high-value chemicals and achieves comprehensive utilization of biomass resources.

DOI: 10.1021/jacs.5c20836

Source: https://pubs.acs.org/doi/abs/10.1021/jacs.5c20836