近日，北京师范大学柳昀哲及其小组的最新研究探明了非空间网格样神经编码的发展跟踪推理和智能。2026年3月25日，国际知名学术期刊《细胞》发表了这一成果。

在203名8-25岁的参与者中，课题组研究人员研究了二维知识图谱的成熟如何支持推理推理和知识同化。内鼻皮层（EC）的网格细胞样编码随着年龄的增长而增强，反映了非空间概念空间的图式表征，并预测了推理推理能力的提高。这些网格状编码也支持内侧前额叶皮层（mPFC）编码二维地图上物体之间的距离关系。当参与者吸收新信息时，他们将其整合到欧共体的现有网格模式中。

此外，这些神经编码的成熟跟踪了现实世界的智力测量，特别是推理能力。他们的发现表明，非空间网格状神经编码的发展为认知发展提供了一种机制解释，将心理学理论与认知地图的基本细胞表征联系起来。

据介绍，皮亚杰的理论认为，儿童发展出结构化的知识图式来推断和吸收新信息，但其潜在的神经机制尚不清楚。

附：英文原文

Title: Development of non-spatial grid-like neural codes tracks inference and intelligence

Author: Yukun Qu, Jianxin Ou, Luoyao Pang, Shuqi Wu, Yuejia Luo, Tim Behrens, Yunzhe Liu

Issue&Volume: 2026-03-25

Abstract: Piaget’s theory posits that children develop structured knowledge schemas for inferring and assimilating new information, yet the underlying neural mechanisms remain unclear. In 203 participants aged 8–25 years, we investigated how maturation of a two-dimensional (2D) knowledge map underpins inferential reasoning and knowledge assimilation. Grid-cell-like codes in the entorhinal cortex (EC) strengthened with age, reflecting schema representations in non-spatial conceptual spaces, and predicted improved inferential reasoning. These grid-like codes also supported the medial prefrontal cortex (mPFC) in encoding distance relationships between objects on the 2D map. As participants assimilated new information, they integrated it into existing grid patterns in the EC. Moreover, the maturation of these neural codes tracked real-world intelligence measures, particularly reasoning abilities. Our findings demonstrate that the development of non-spatial grid-like neural codes offers a mechanistic account of cognitive development, bridging psychological theory with a fundamental cellular representation of the cognitive map.

DOI: 10.1016/j.cell.2026.02.028

Source: https://www.cell.com/cell/abstract/S0092-8674(26)00266-7