近日，清华大学叶钢团队报道了在氢键框架中设计动态质子“枢纽”以实现超质子导电性。2026年2月25日，《德国应用化学》杂志发表了这一成果。

模拟生物学中的协同质子传导对合成材料而言仍是巨大挑战。

研究组报道了一种在氢键有机框架内构建动态质子"枢纽"的策略。这些枢纽是由铵根与磺酸基团通过电荷辅助氢键形成的超分子次级结构单元，被预先设计在框架中以引导质子传输。所得铵-磺酸基氢键有机框架BPDS_NH4在90°C、90%相对湿度条件下展现出0.21 S cm^-1的优异质子传导率。

这种卓越性能源于质子枢纽的双重功能：其高电荷密度和亲水性为溶剂化质子簇的运载传输提供了高速通道，同时每个枢纽内部致密的动态氢键网络为超快格罗特斯质子跳跃构建了受限空间。通过活化能分析和氢氘同位素效应验证，这两个过程实现了协同耦合。该研究确立了超分子质子枢纽的构建方法，为理性设计先进质子传导材料提供了通用蓝图。

附：英文原文

Title: Engineering Dynamic Proton “Hubs” in Hydrogen-Bonded Frameworks for Superprotonic Conductivity

Author: Yilin Luo, Yi Su, Xiaojun Ding, Yi Xie, Pengling Huang, Gang Ye

Issue&Volume: 2026-02-25

Abstract: Mimicking the synergistic proton conduction in biology remains a formidable challenge for synthetic materials. Here, we report a strategic approach by engineering dynamic proton “hubs” within hydrogen-bonded organic frameworks (HOFs). These hubs are supramolecular secondary building units (SSBUs) formed by charge-assisted hydrogen bonds between ammonium and sulfonate groups, which are programmed into the frameworks to direct proton traffic. The resulting ammonium-sulfonate HOF, BPDS_NH4, exhibits a highly competitive proton conductivity of 0.21 S cm1 (90°C, 90% RH). The exceptional performance is governed by the dual function of the proton hubs: their high charge density and hydrophilicity create a highway for vehicular transport of solvated proton clusters (H+(H2O)n), while the dense, dynamic H-bonded network within each hub serves as a confined arena for ultrafast Grotthuss hopping. These processes are synergistically coupled, as verified by activation energy analysis and H/D isotope effect. This work establishes the construction of supramolecular proton hubs as a versatile blueprint for the rational design of advanced proton-conducting materials.

DOI: 10.1002/anie.202525282

Source: https://onlinelibrary.wiley.com/doi/10.1002/anie.202525282