中山大学薛铭团队近日研究了具有亚纳米通道的多元MOF中空纤维膜用于芳烃分离。2025年5月29日出版的《德国应用化学》杂志发表了这项成果。

金属有机框架（MOF）膜在分子分离方面表现出巨大的潜力，但实现精确的孔径调节仍然是一个相当大的挑战，通常需要为每次目标分离合成不同的MOF结构。在此，通过利用配体的异质空间分布，制造了第一个具有精确调谐亚纳米通道的多元MOF（MTV-MOF）中空纤维膜，其中减少的配位能垒驱动了交替的窄（局部路径受限）和宽通道的形成，同时解决了膜分离中的关键渗透选择性权衡问题。 

通过结合密度泛函理论计算、分子动力学模拟和数学建模，对交替窄宽通道结构进行了系统研究，并通过低剂量高分辨率扫描透射电子显微镜和定量吸附分析提供了直接的实验验证。这些MTV-MOF膜证明了选择性分离芳烃的能力，实现了高度选择性的分离，同时减少了分子传输障碍，为工业分离过程提供了巨大的潜力。

附：英文原文

Title: Multivariate MOF Hollow Fiber Membranes with Precision-Tuned Subnanometer Channels toward Aromatic Hydrocarbon Separation

Author: Zhen Chen, Bin Li, Ying Liu, Zi-Meng Xu, Xiao-Feng Zhong, Pan-Pan Zhang, Ling-Mei Liu, Yi Li, MING XUE, Xiao-Ming Chen

Issue&Volume: 2025-05-29

Abstract: Metal-organic framework (MOF) membranes exhibit great potential for molecular separations, but it remains a considerable challenge to achieve precise pore aperture regulation, typically requiring the synthesis of distinct MOF structures for each targeted separation. Herein, the first multivariate MOF (MTV-MOF) hollow fiber membranes with precision-tuned subnanometer channels have been fabricated by leveraging the heterogeneous spatial distribution of ligands, where reduced coordination energy barriers drive the formation of alternating narrow (local-path limited) and wide channels, simultaneously addressing the critical permeability-selectivity trade-off in membrane separations. The alternating narrow-wide channel architecture has been systematically investigated through combined density functional theory calculation, molecular dynamics simulation and mathematical modeling, with direct experimental validation provided by low-dose high-resolution scanning transmission electron microscopy and quantitative adsorption analysis. These MTV-MOF membranes demonstrated the ability to selectively separate aromatic hydrocarbons achieving highly selective separation while reduce the molecular transport barriers, offering significant potential for industrial separation processes.

DOI: 10.1002/anie.202508510

Source: https://onlinelibrary.wiley.com/doi/10.1002/anie.202508510