近日，英国洛桑研究教授Matthew J. Paul及其小组的最新研究探明了膜透性海藻糖6-磷酸前体喷雾在田间试验中提高小麦产量。2025年4月29日出版的《自然—生物技术》发表了这项成果。

本研究表明，在多种农业条件下，通过定时微剂量的植物渗透性、阳光激活的T6P信号前体DMNB-T6P，小麦产量得到了提高。在水分充足和缺水的条件下超过4多年来，DMNB-T6P对三个优良品种的产量有促进作用。产量的增加比育种计划的平均年遗传收益大一个数量级，而且没有额外的水或肥料。机制分析表明，这些益处来自于二氧化碳固定和线性电子流的增加（“强度”），以及淀粉胚乳体积的增加、颗粒筛管发育的增强和淀粉、氨基酸和蛋白质合成基因的上调（“汇”）。这些数据证明了一种逐步变化的、可扩展的、对环境有净效益的技术，可以为各种主要谷类作物提供可持续的产量提高。

研究人员表示，海藻糖6-磷酸（T6P）是植物中促进生长的内源性糖信号，但它不能直接引入作物或完全遗传控制。

附：英文原文

Title: Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials

Author: Griffiths, Cara A., Xue, Xiaochao, Miret, Javier A., Salvagiotti, Fernando, Acevedo-Siaca, Liana G., Gimeno, Jacinta, Reynolds, Matthew P., Hassall, Kirsty L., Halsey, Kirstie, Puranik, Swati, Oszvald, Maria, Kurup, Smita, Davis, Benjamin G., Paul, Matthew J.

Issue&Volume: 2025-04-29

Abstract: Trehalose 6-phosphate (T6P) is an endogenous sugar signal in plants that promotes growth, yet it cannot be introduced directly into crops or fully genetically controlled. Here we show that wheat yields were improved using a timed microdose of a plant-permeable, sunlight-activated T6P signaling precursor, DMNB-T6P, under a variety of agricultural conditions. Under both well-watered and water-stressed conditions over 4years, DMNB-T6P stimulated yield of three elite varieties. Yield increases were an order of magnitude larger than average annual genetic gains of breeding programs and occurred without additional water or fertilizer. Mechanistic analyses reveal that these benefits arise from increased CO2 fixation and linear electron flow (‘source’) as well as from increased starchy endosperm volume, enhanced grain sieve tube development and upregulation of genes for starch, amino acid and protein synthesis (‘sink’). These data demonstrate a step-change, scalable technology with net benefit to the environment that could provide sustainable yield improvements of diverse staple cereal crops.

DOI: 10.1038/s41587-025-02611-1

Source: https://www.nature.com/articles/s41587-025-02611-1