北京化工大学谭天伟研究小组揭示了耦合光催化还原和生物合成实现可持续的CO₂升级循环。2025年2月26日出版的《德国应用化学》发表了这项成果。

在此，课题组研究人员报道了一种串联光催化-生物合成策略，用于有效地将CO₂还原为高能量的蔗糖或α-法尼烯。首先，在过渡金属掺杂ZnO （M-ZnO）上优化CO₂光催化还原为CH₄。制备的Ni-ZnO优先还原CO₂为CH₄，产率为1539.1 μmol g^-1 h^-1，由于独特的界面结构 (Znδ+−O−Niβ+)，选择性高达90%。随后，对buryatense甲基微生物5GB1C进行基因工程改造，以光催化法制得的CH₄为唯一碳源，其效价分别为96.3和43.9 mg L^-1。本研究为二氧化碳作为碳源合成长链化合物提供了一条绿色、低能量的途径，为解决长期能源需求和可持续的二氧化碳升级回收提供了新的思路。

研究人员表示，将二氧化碳（CO₂）升级为长链化合物在缓解环境问题和获得增值原料方面引起了相当大的关注，但仍然是一个巨大的挑战。

附：英文原文

Title: Coupling Photocatalytic Reduction and Biosynthesis towards Sustainable CO₂ Upcycling

Author: Mengjie Yu, Maolong Li, Xinzhe Zhang, Zhen Ge, Enze Xu, Lei Wang, Boyu Yin, Yibo Dou, Yusen Yang, Xin Zhang, Qiang Fei, Min Wei, Tianwei Tan

Issue&Volume: 2025-02-26

Abstract: Upcycling carbon dioxide (CO₂) into long-chain compounds has attracted considerable attention with respect to mitigating environmental problems and obtaining value-added feedstocks, but remains a great challenge. Herein, we report a tandem photocatalysis-biosynthesis strategy for efficient CO₂ reduction to energy-rich sucrose or α-farnesene. Firstly, photocatalytic reduction of CO₂ to CH₄ was optimized over the transitional metal doped ZnO (M-ZnO). The as-prepared Ni-ZnO preferentially reduces CO₂ to CH₄ with a production rate of 1539.1 μmol g^-1 h^-1 and a selectivity of 90%, owing to the unique interface structure (Znδ+−O−Niβ+). Subsequently, Methylomicrobium buryatense 5GB1C was genetically engineered to produce sucrose or α-farnesene using photocatalytically-obtained CH₄ as the sole carbon source, with a titer of 96.3 and 43.9 mg L^-1, respectively. This study provides a green, low-energy pathway for the synthesis of long-chain compounds from CO₂ as the carbon source, which sheds new light on tackling long-term energy demands and sustainable CO₂ upcycling.

DOI: 10.1002/anie.202423995

Source: https://onlinelibrary.wiley.com/doi/10.1002/anie.202423995