对无反应个体的亲社会行为的神经基础,这一成果由美国加利福尼亚大学
在这项研究中,研究人员证明了老鼠对无反应的同种动物表现出类似救助的社会行为,其特点是强烈的身体接触和对接受者的面部和口腔区域的梳理,这加速了它们从无反应中恢复过来。研究人员确定内侧杏仁核(MeA)是编码他人无反应状态并驱动这种头部导向的身体接触的关键区域。值得注意的是,对无反应的同种个体的行为反应不同于对清醒的、有压力的个体的行为反应,这些反应在MeA中有不同的表现。这些发现揭示了对无反应个体的亲社会反应的神经机制。
研究人员表示,人类经常采取行动来帮助那些经历无反应的人,比如短暂的意识丧失。其他动物对无反应的同种动物是如何反应的,以及驱动这种行为的神经机制在很大程度上仍未被探索。
附:英文原文
Title: A neural basis for prosocial behavior toward unresponsive individuals
Author: Fangmiao Sun, Ye Emily Wu, Weizhe Hong
Issue&Volume: 2025-02-21
Abstract: Humans often take actions to assist others experiencing unresponsiveness, such as transient loss of consciousness. How other animals react to unresponsive conspecifics—and the neural mechanisms driving such behaviors—remain largely unexplored. In this study, we demonstrated that mice exhibit rescue-like social behaviors toward unresponsive conspecifics, characterized by intense physical contact and grooming directed at the recipient’s facial and mouth areas, which expedite their recovery from unresponsiveness. We identified the medial amygdala (MeA) as a key region that encodes the unresponsive state of others and drives this head-directed physical contact. Notably, the behavioral responses toward unresponsive conspecifics differed from those directed at awake, stressed individuals, and these responses were differentially represented in the MeA. These findings shed light on the neural mechanisms underlying prosocial responses toward unresponsive individuals.
DOI: adq2679
Source: https://www.science.org/doi/10.1126/science.adq2679