近日，法国格勒诺布尔阿尔卑斯大学Uzu, Gaelle团队研究了欧洲大气颗粒的氧化电位和暴露情景。相关论文于2025年10月22日发表在《自然》杂志上。

大气颗粒物（PM）是全球关注的一个公共卫生问题，目前是根据其质量浓度进行管制的。然而，越来越多的人认为，质量浓度可能无法完全反映与其健康影响相关的PM的物理化学性质。因此，有人建议进一步调查这一指标作为PM健康影响的明确指标是否足够。欧洲关于空气质量的新法规将氧化电位（OP）作为一项建议参数，在监测点进行监测，以进一步探索有关PM反应性和健康影响的信息。

研究组建立了一个数据库，其中包含了来自欧洲43个地点的近11,500个OP测量值，这些测量值用两种最常见的OP分析方法（OPAA和OPDTT）进行了分析，并采用了标准化协议。研究组发现整个欧洲的OP具有很高的空间变异性，受场地类型（如城市或农村）的强烈影响。考虑到OP和PM质量表明，可能需要考虑进一步改善城市空气质量，特别是在道路附近，PM10的体积OP超过背景水平2.4至3.1倍，具体取决于分析应用。对缓解战略的分析表明，交通是有效减少城市OP的关键因素，而交通和生物质燃烧产生的PM也需要全面减少，以满足世界卫生组织的质量准则。虽然OP对健康影响的流行病学证据仍在不断发展，但他们的发现可能有助于解释未来的工作。

附：英文原文

Title: Oxidative potential of atmospheric particles in Europe and exposure scenarios

Author: Tassel, Ccile, Jaffrezo, Jean-Luc, Dominutti, Pamela, Daellenbach, Kaspar R., Darfeuil, Sophie, Elazzouzi, Rhabira, Laj, Paolo, Marsal, Anouk, Mhadhbi, Takoua, Dinh, Vy Ngoc Thuy, Voiron, Cline, Houdier, Stephan, Durif, Marc, Chatain, Mlodie, Francony, Florie, Cozic, Julie, Salque Moreton, Guillaume, Le Quilleuc, Meryll, Ghersi, Vronique, Gille, Grgory, Mesbah, Boualem, Stratigou, Evdokia, Zublena, Manuela, Dimoz, Henri, Alastuey, Andrs, DAnna, Barbara, Marchand, Nicolas, Conil, Sbastien, Gros, Valrie, van Os, Marloes F., Salma, Imre, Mihalopoulos, Nikolaos, Monik, Gria, Depina, Katja, Styszko, Katarzyna, Hglin, Christoph, Querol, Xavier, Prvt, Andr S. H., Favez, Olivier, Siroux, Valrie, Uzu, Galle

Issue&Volume: 2025-10-22

Abstract: Atmospheric particulate matter (PM), a public health concern worldwide, is at present regulated according to its mass concentration1. However, it is increasingly thought that mass concentration may not fully capture the physicochemical properties of PM linked to its health impact2. Consequently, it has been suggested to further investigate the adequacy of this metric as an unequivocal indicator of PM health effects3,4,5. The new European regulation on air quality introduced oxidative potential (OP) as a recommended parameter to be monitored at supersites1, to explore further deciphering information about PM reactivity and health impacts6,7. Here we use a database of almost 11,500 OP measurements from 43 locations across parts of Europe that were analysed with the two most commonly used OP assays8, OPAA and OPDTT, with a standardized protocol9,10. We find high spatial variability of OP across Europe, strongly influenced by site type, such as urban or rural. Accounting for OP alongside PM mass suggests that further improvements in urban air quality may require consideration, particularly near roads, where volumetric OP of PM10 exceeds background levels by a factor of 2.4 to 3.1, depending on the assay used. Analysis of mitigation strategies shows that traffic is a key source to target for effectively reducing OP in cities, whereas comprehensive reductions in PM from both traffic and biomass burning are required to also meet World Health Organization mass guidelines. Although the epidemiological evidence for OP health impacts is still evolving2,8, our findings may help inform the interpretation of future work.

DOI: 10.1038/s41586-025-09666-9

Source: https://www.nature.com/articles/s41586-025-09666-9