在这里，该课题组人员报道了自发的预热室1 （spoh1）突变体的鉴定，该突变体在没有外部宿主信号的情况下形成预热室。在编码尿苷二磷酸-葡萄糖基转移酶UGT72B1的基因中，spoh1含有一个点突变，UGT72B1是一种葡萄糖化酶，从而使酚类HIFs失活。PjUGT72B1与宿主拟南芥同源物具有不同的底物特异性。将PjUGT72B1引入拟南芥中，降低了嗜盐前诱导活性，表明UGT72B1调控宿主嗜盐诱导。他们的研究结果表明，龙牙科半寄生植物通过内源性HIFs的糖基化进化出了亲属回避机制。
研究人员表示，寄生植物很少攻击自己，这表明亲缘回避机制的存在。在根寄生植物日本芽孢杆菌（Phtheirospermum japonicum）中，芽孢杆菌的形成是由寄主分泌的芽孢诱导因子（HIFs）触发的，但它对自己的分泌物没有反应。
附：英文原文
Title: Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants
Author: Lei Xiang, Songkui Cui, Simon B. Saucet, Moe Takahashi, Shoko Inaba, Bing Xie, Mario Schilder, Shota Shimada, Mengqi Cui, Yanmei Li, Mutsumi Watanabe, Yuki Tobimatsu, Harro J. Bouwmeester, Takayuki Tohge, Ken Shirasu, Satoko Yoshida
Issue&Volume: 2025-10-23
Abstract: Parasitic plants rarely attack themselves, suggesting the existence of a kin-avoidance mechanism. In the root parasitic plant Phtheirospermum japonicum, prehaustorium formation is triggered by host-secreted haustorium-inducing factors (HIFs), but it is unresponsive to its own exudates. Here we report the identification of the spontaneous prehaustorium 1 (spoh1) mutant, which forms prehaustoria without external host signals. spoh1 harbors a point mutation in the gene encoding uridine diphosphate–glucosyltransferase UGT72B1, an enzyme that glucosylates and thereby inactivates phenolic HIFs. PjUGT72B1 has a different substrate specificity than its ortholog of the host Arabidopsis. Introduction of PjUGT72B1 into Arabidopsis reduced prehaustorium induction activity, indicating that UGT72B1 regulates haustorium induction by hosts. Our findings suggest that Orobanchaceae hemiparasitic plants have evolved kin-avoidance mechanisms through the glucosylation of endogenous HIFs.
DOI: adx8220
Source: https://www.science.org/doi/10.1126/science.adx8220