中国科学院兰州化学物理研究所吴立朋团队，报道了羧酸及其衍生物的脱羧和脱羧硼酸化研究进展。相关研究成果发表在2024年9月18日出版的国际学术期刊《中国化学》。

硼酸酯因其在创建C-C和C-X键方面的多功能性，而在合成和制药行业受到高度重视。它们还被用作化学转化的催化剂，以及材料科学中的刺激响应材料。一些烷基硼酸酯本身在药物化学中也显示出有前景的应用。

在过去的几十年里，化学家们一直致力于开发合成硼酸酯的新方法或新原料。羧酸及其衍生物因其易得性或天然丰度、结构多样性和化学稳定性而成为特权化学实体。因此，羧酸及其衍生物向烷基/芳基硼酸酯的转化，在过去十年中得到了快速发展。

该文综述了羧酸及其衍生物脱羧和脱羰硼酰化，制备芳基和烷基硼酸酯的最新进展。

附：英文原文

Title: Decarboxylative and Decarbonylative Borylation of Carboxylic Acids and Their Derivatives†

Author: Xiaoxian Li, Lipeng Wu

Issue&Volume: 2024-09-18

Abstract: Boronate esters are highly valued in synthetic and pharmaceutical industries for their versatility in creating C—C and C—X bonds. They also find applications as catalysts in chemical transformations as well as stimuli-responsive materials in materials science. Some alkyl boronates themselves also show promising applications in medicinal chemistry. In the past few decades, chemists have been devoted to developing new methods or new starting materials for synthesizing boronate esters. Carboxylic acids and their derivatives are privileged chemical entities due to their readily availability or natural abundance, structural diversity, and chemical stability. Hence, the transformation of carboxylic acid and their derivatives to alkyl/aryl boronate esters has seen its fast development in the past decade. This review summarized the state-to-art development of decarboxylative and decarbonylative borylation of carboxylic acids and their derivatives to aryl and alkyl boronate esters.

DOI: 10.1002/cjoc.202400616

Source: https://onlinelibrary.wiley.com/doi/full/10.1002/cjoc.202400616