美国加利福尼亚大学Phillip B. Messersmith团队报道了外科、消费和工业用可回收聚α-硫辛酸胶粘剂。相关研究成果于2024年8月23日发表在《科学》。

聚合物粘合剂在许多医疗、消费和工业产品中起着重要作用。α-硫辛酸（αLA）聚合物具有满足多功能和环保粘合剂需求的潜力，但其性能受到自发解聚的困扰。

研究人员报告了一系列稳定的αLA聚合物粘合剂，可以针对各种医疗或非医疗用途量身定制，并以闭环方式可持续生产和回收。

单体组成的微小变化提供了一种在干燥和潮湿条件下功能良好的压敏粘合剂，以及一种强度与传统环氧树脂相当的结构粘合剂。αLA外科强力胶成功密封小鼠羊膜囊破裂，将胎儿存活率从0提高到100%。

附：英文原文

Title: Recyclable surgical, consumer, and industrial adhesives of poly(α-lipoic acid)

Author: Subhajit Pal, Jisoo Shin, Kelsey DeFrates, Mustafa Arslan, Katelyn Dale, Hannah Chen, Dominic Ramirez, Phillip B. Messersmith

Issue&Volume: 2024-08-23

Abstract: Polymer adhesives play an important role in many medical, consumer, and industrial products. Polymers of α-lipoic acid (αLA) have the potential to fulfill the need for versatile and environmentally friendly adhesives, but their performance is plagued by spontaneous depolymerization. We report a family of stabilized αLA polymer adhesives that can be tailored for a variety of medical or nonmedical uses and sustainably sourced and recycled in a closed-loop manner. Minor changes in monomer composition afforded a pressure-sensitive adhesive that functions well in dry and wet conditions, as well as a structural adhesive with strength equivalent to that of conventional epoxies. αLA surgical superglue successfully sealed murine amniotic sac ruptures, increasing fetal survival from 0 to 100%.

DOI: ado6292

Source: https://www.science.org/doi/10.1126/science.ado6292