中国科学院大连化学物理研究所陈庆安团队，报道了烷基溴催化转移氯化对卤代有机污染物的再利用。相关研究成果发表在2024年6月6日出版的国际知名学术期刊《自然—化学》。

卤代有机污染物由于其高毒性、持久性和生物累积性，正在造成重大的环境和人类健康危机。需要采取紧急行动，制定减少和再利用HOPs的有效方法。尽管目前的战略主要侧重于HOPs的退化，但重新利用它们是一种替代方法，尽管这是一项具有挑战性的任务。

该文中，研究人员发现烷基溴可以用烷基氯作为氯源作为氯转移的催化剂。研究证明了这种方法具有广泛的底物范围，并成功地将其应用于重复使用HOPs，包括二氯二苯基三氯乙烷、六溴环十二烷、氯化石蜡、氯甲基聚苯乙烯和聚氯乙烯。此外，证明了使用PVC和六溴环十二烷可以合成必需的非甾体抗炎药，并且证明了PVC废物可以直接用作氯化剂。

总的来说，这种方法为重新调整HOPs的用途提供了一种很有前景的战略。

附：英文原文

Title: Repurposing of halogenated organic pollutants via alkyl bromide-catalysed transfer chlorination

Author: Liu, Heng, Ji, Ding-Wei, Mei, Yong-Kang, Liu, Yan, Liu, Chang-Hui, Wang, Xiao-Yu, Chen, Qing-An

Issue&Volume: 2024-06-06

Abstract: Halogenated organic pollutants (HOPs) are causing a significant environmental and human health crisis due to their high levels of toxicity, persistence and bioaccumulation. Urgent action is required to develop effective approaches for the reduction and reuse of HOPs. Whereas current strategies focus primarily on the degradation of HOPs, repurposing them is an alternative approach, albeit a challenging task. Here we discover that alkyl bromide can act as a catalyst for the transfer of chlorine using alkyl chloride as the chlorine source. We demonstrate that this approach has a wide substrate scope, and we successfully apply it to reuse HOPs that include dichlorodiphenyltrichloroethane, hexabromocyclododecane, chlorinated paraffins, chloromethyl polystyrene and poly(vinyl chloride) (PVC). Moreover, we show that the synthesis of essential non-steroidal anti-inflammatory drugs can be achieved using PVC and hexabromocyclododecane, and we demonstrate that PVC waste can be used directly as a chlorinating agent. Overall, this methodology offers a promising strategy for repurposing HOPs.

DOI: 10.1038/s41557-024-01551-8

Source: https://www.nature.com/articles/s41557-024-01551-8