加拿大多伦多大学Alán Aspuru-Guzik团队报道了有机激光发射器的非定域、非同步、闭环发现。相关研究成果于2024年5月17日发表在《科学》。

当代材料的发现需要复杂的合成、配方和表征序列，这些序列通常跨越多个地点，并具有专业知识或仪器。

为了加快这些工作流程，研究人员提出了一种基于云的策略，该策略支持异地和异步设计-测试-分析周期。研究人员通过探索有机固态激光器的分子增益材料作为分子光电子的前沿应用，并展示了这种方法。

由基于云的人工智能实验规划师精心策划，分布式机器人合成和在线特性表征，发现了21种最先进的新材料。Gram规模的合成最终能够在薄膜器件中验证同类最佳的受激发射。

该工作流程展示了全球五个实验室的异步集成，为科学发现的异地化和民主化提供了蓝图。

附：英文原文

Title: Delocalized, asynchronous, closed-loop discovery of organic laser emitters

Author: Felix Strieth-Kalthoff, Han Hao, Vandana Rathore, Joshua Derasp, Théophile Gaudin, Nicholas H. Angello, Martin Seifrid, Ekaterina Trushina, Mason Guy, Junliang Liu, Xun Tang, Masashi Mamada, Wesley Wang, Tuul Tsagaantsooj, Cyrille Lavigne, Robert Pollice, Tony C. Wu, Kazuhiro Hotta, Leticia Bodo, Shangyu Li, Mohammad Haddadnia, Agnieszka Woos, Rafa Roszak, Cher Tian Ser, Carlota Bozal-Ginesta, Riley J. Hickman, Jenya Vestfrid, Andrés Aguilar-Granda, Elena L. Klimareva, Ralph C. Sigerson, Wenduan Hou, Daniel Gahler, Slawomir Lach, Adrian Warzybok, Oleg Borodin, Simon Rohrbach, Benjamin Sanchez-Lengeling, Chihaya Adachi, Bartosz A. Grzybowski, Leroy Cronin, Jason E. Hein, Martin D. Burke, Alán Aspuru-Guzik

Issue&Volume: 2024-05-17

Abstract: Contemporary materials discovery requires intricate sequences of synthesis, formulation, and characterization that often span multiple locations with specialized expertise or instrumentation. To accelerate these workflows, we present a cloud-based strategy that enabled delocalized and asynchronous design-make-test-analyze cycles. We showcased this approach through the exploration of molecular gain materials for organic solid-state lasers as a frontier application in molecular optoelectronics. Distributed robotic synthesis and in-line property characterization, orchestrated by a cloud-based artificial intelligence experiment planner, resulted in the discovery of 21 new state-of-the-art materials. Gram-scale synthesis ultimately allowed for the verification of best-in-class stimulated emission in a thin-film device. Demonstrating the asynchronous integration of five laboratories across the globe.

DOI: adk9227

Source: https://www.science.org/doi/10.1126/science.adk9227