清华大学杜伟团队报道了单晶有序宏微孔金属有机骨架高产率合成的通用方法。相关研究成果于2024年11月4日发表在《美国化学会杂志》。

尽管与常规MOFs相比，单晶有序大微孔MOFs（SOM MOFs）具有优异的性能，但由于缺乏通用和高产的制备方案，它们的进一步发展受到了阻碍。

该研究介绍了一种创新的通用制造方法，可以很容易地解决前体稳定和结晶调节这两个主要挑战，从而能够以高产率高效合成各种SOM MOFs。值得注意的是，该方法成功地制备了SOM-ML-88A，这是一种新型MOF，在水和酸性溶液中都表现出卓越的稳定性，是之前SOM-MOF研究中前所未有的显著成就。

SOM-MIL-88A在吸附、催化、固定化酶和复合生物传感方面比传统MIL-88A的性能呈指数级提高。此外，该多功能方案已成功应用于合成SOM-HKUST-1和SOM-ZIF-8，从而显著提高了产率（与之前报道的方案相比，分别增加了约10倍和2倍）。

该突破性的成就标志着，在制备具有定制性能的各种SOM MOFs方面取得了关键进展，为MOFs的未来研究带来了令人兴奋的前景。

附：英文原文

Title: A Universal Approach for High-Yield Synthesis of Single-Crystalline Ordered Macro-Microporous Metal–Organic Frameworks

Author: Zhiqiang Zou, Zhuoyang Du, Lingmei Dai, Dehua Liu, Wei Du

Issue&Volume: November 4, 2024

Abstract: Despite the excellent properties of single-crystalline ordered macro-microporous MOFs (SOM-MOFs) compared to conventional MOFs, their further development has been hindered by the lack of versatile and high-yielding preparation protocols. This study introduces an innovative universal fabrication method that can easily solve the two major challenges of precursor stabilization and crystallization modulation, enabling the efficient synthesis of various SOM-MOFs with high yields. Notably, our approach has successfully yielded SOM-MIL-88A, a novel MOF showcasing exceptional stability in both water and acidic solutions, a remarkable achievement unprecedented in prior SOM-MOF research. SOM-MIL-88A has demonstrated exponentially improved performance over conventional MIL-88A in adsorption, catalysis, immobilized enzymes, and composite biosensing. Furthermore, our versatile protocol has been successfully applied to synthesize SOM-HKUST-1 and SOM-ZIF-8, resulting in significantly improved yields (increase by about 10-fold and 2-fold, respectively, compared to the previously reported protocol). This groundbreaking achievement marks a pivotal advancement in the preparation of diverse SOM-MOFs with tailored properties, presenting exciting prospects for future research on MOFs.

DOI: 10.1021/jacs.4c11243

Source: https://pubs.acs.org/doi/abs/10.1021/jacs.4c11243