研究人员对187个物种的细胞内免疫受体库特征与性状数据进行比较的分析显示，在野生植物中，分子防御库的大小与生长呈负相关。相比之下，研究人员未能在农业植物中发现生长与防御之间的权衡证据。该跨物种方法突出了防御投资在塑造生态性状变异中的核心作用及其对驯化的敏感性。
据介绍，考虑到病原对宿主造成的负面适应性影响，抗性带来的益处应当是普遍的。然而，不同植物物种在核苷酸结合富含亮氨酸重复（NLR）受体的数量上存在显著差异，这些受体是防御的核心。生长与防御权衡假说预测防御投资所带来的成本，从而产生这些性状的变异。
附：英文原文
Title: A trade-off between investment in molecular defense repertoires and growth in plants
Author: Michael Giolai, Anna-Liisa Laine
Issue&Volume: 2024-11-08
Abstract: Given the negative fitness effects that pathogens impose on their hosts, the benefits of resistance should be universal. However, there is marked variation across plant species in the number of nucleotide-binding leucine-rich repeat receptors, which form a cornerstone of defense. The growth–defense trade-off hypothesis predicts costs associated with defense investment to generate variation in these traits. Our analysis comparing features of the intracellular immune-receptor repertoires with trait data of 187 species shows that in wild plants, the size of the molecular defense repertoire correlates negatively with growth. By contrast, we do not find evidence for a growth–defense trade-off in agricultural plants. Our cross-species approach highlights the central role of defense investment in shaping ecological trait variation and its sensitivity to domestication.
DOI: adn2779
Source: https://www.science.org/doi/10.1126/science.adn2779