安徽大学李漫波团队报道了Au11胺化的预组织氮位点，一种实现金属纳米团簇精确功能化的通用策略。相关研究成果发表在2023年5月26日出版的《美国化学会杂志》。

原子精密金属纳米团簇由于其独特的结构和性能而受到极大的关注。尽管这种纳米材料的合成方法已经得到了很好的发展，但对合成的金属纳米团簇进行精确功能化的方法极其有限，阻碍了它们的界面改性和相关性能的提高。

该文中，研究人员开发了一种酰胺化策略，用于基于预有机氮位点的Au11纳米簇的精确功能化。纳米团簇酰胺化没有改变Au11核中金原子的数量及其与表面配体的键合模式，但通过引入官能团和手性略微改变了金原子的排列，因此代表了一种相对温和的金属纳米团簇修饰方法。Au11纳米团簇的稳定性和氧化势垒也相应地得到改善。开发的方法将是金属纳米团簇精确功能化的一种可推广的策略。

附：英文原文

Title: Preorganized Nitrogen Sites for Au11 Amidation: A Generalizable Strategy toward Precision Functionalization of Metal Nanoclusters

Author: Ying Zhang, Sheng-Rong He, Ying Yang, Tai-Song Zhang, Ze-Min Zhu, Wenwen Fei, Man-Bo Li

Issue&Volume: May 26, 2023

Abstract: Atomically precise metal nanoclusters have received tremendous attention due to their unique structures and properties. Although synthetic approaches to this kind of nanomaterial have been well developed, methods toward precision functionalization of the as-synthesized metal nanoclusters are extremely limited, hindering their interfacial modification and related performance improvement. Herein, an amidation strategy has been developed for the precision functionalization of the Au11 nanocluster based on preorganized nitrogen sites. The nanocluster amidation did not change the number of gold atoms in the Au11 kernel and their bonding mode to the surface ligands but slightly modified the arrangement of gold atoms with the introduction of functionality and chirality, thus representing a relatively mild method for the modification of metal nanoclusters. The stability and oxidation barrier of the Au11 nanocluster are also improved accordingly. The method developed here would be a generalizable strategy for the precision functionalization of metal nanoclusters.

DOI: 10.1021/jacs.3c01961

Source: https://pubs.acs.org/doi/10.1021/jacs.3c01961