北京大学高家红课题组通过中国人类连接组计划增加连接组学的多样性。相关论文于2022年12月19日在线发表在《自然—神经科学》杂志上。

Title: Increasing diversity in connectomics with the Chinese Human Connectome Project

Author: Ge, Jianqiao, Yang, Guoyuan, Han, Meizhen, Zhou, Sizhong, Men, Weiwei, Qin, Lang, Lyu, Bingjiang, Li, Hai, Wang, Haobo, Rao, Hengyi, Cui, Zaixu, Liu, Hesheng, Zuo, Xi-Nian, Gao, Jia-Hong

Issue&Volume: 2022-12-19

Abstract: Cultural differences and biological diversity play important roles in shaping human brain structure and function. To date, most large-scale multimodal neuroimaging datasets have been obtained primarily from people living in Western countries, omitting the crucial contrast with populations living in other regions. The Chinese Human Connectome Project (CHCP) aims to address these resource and knowledge gaps by acquiring imaging, genetic and behavioral data from a large sample of participants living in an Eastern culture. The CHCP collected multimodal neuroimaging data from healthy Chinese adults using a protocol comparable to that of the Human Connectome Project. Comparisons between the CHCP and Human Connectome Project revealed both commonalities and distinctions in brain structure, function and connectivity. The corresponding large-scale brain parcellations were highly reproducible across the two datasets, with the language processing task showing the largest differences. The CHCP dataset is publicly available in an effort to facilitate transcultural and cross-ethnic brain–mind studies.

DOI: 10.1038/s41593-022-01215-1

Source: https://www.nature.com/articles/s41593-022-01215-1