南方科技大学刘柳团队开发了一种合成有机磷化合物的简便方法。相关研究成果发表在2022年1月18日出版的《美国化学会杂志》。

有机磷化合物（OPCs）由于从合成化学到材料和生物科学的广泛应用，在过去的几十年中获得了极大的兴趣。

该文中，研究人员描述了一种实用且通用的方法，通过一个关键的桥阴离子[P(CN)2]将白磷（P4）转化为具有高P原子经济性的有用OPCs。该阴离子可通过电化学过程直接从P4制备，重量为克。以两步方式从P4容易地获得涉及亚膦、环磷酰胺和磷内酯的各种OPCs。

该方法对未来在实验室和工业环境中制备OPCs具有重大影响。

附：英文原文

Title: Facile Synthesis of the Dicyanophosphide Anion via Electrochemical Activation of White Phosphorus: An Avenue to Organophosphorus Compounds

Author: Yanbo Mei, Zeen Yan, Liu Leo Liu

Issue&Volume: January 18, 2022

Abstract: Organophosphorus compounds (OPCs) have gained tremendous interest in the past decades due to their wide applications ranging from synthetic chemistry to materials and biological sciences. We describe herein a practical and versatile approach for the transformation of white phosphorus (P4) into useful OPCs with high P atom economy via a key bridging anion [P(CN)2]. This anion can be prepared on a gram scale directly from P4 through an electrochemical process. A variety of OPCs involving phosphinidenes, cyclophosphanes, and phospholides have been made readily accessible from P4 in a two-step manner. Our approach has a significant impact on the future preparation of OPCs in laboratory and industrial settings.

DOI: 10.1021/jacs.1c11087

Source: https://pubs.acs.org/doi/10.1021/jacs.1c11087