美国加州大学Gang-yu Liu团队报道了用设计方法制备组织手性结构。相关研究成果发表在2022年1月10日出版的《美国化学会杂志》。

表面上的组织手性由于其科学重要性和潜在的应用，一直是化学和材料科学的研究热点。目前在表面上产生有组织手性结构的方法主要基于分子的自组装。手性结构虽然强大，但仅限于表面反应热力学所决定的结构。

该文中，研究人员介绍了一种方法，通过设计创造具有纳米精度的组织手性设计。利用基于原子力显微镜的纳米光刻技术，结合所选择的表面化学，以纳米精度制备各种手性结构，从简单的螺旋线和纳米特征阵列到复杂的分层手性结构。尺寸、几何形状和组织手性是以确定性的方式实现的，对设计具有高保真度。

该文报道的概念和方法为研究人员提供了一种新的、通用的方法来进行组织手性化学，通过设计手性结构具有固有的优势。研究结果为手性纳米材料的制备和识别开辟了新的应用前景，包括对映选择性催化、分离和结晶，以及需要特定偏振辐射的光学器件。

附：英文原文

Title: Production of Organizational Chiral Structures by Design

Author: Audrey R. Sulkanen, Minyuan Wang, Logan A. Swartz, Jaeuk Sung, Gang Sun, Jeffrey S. Moore, Nancy R. Sottos, Gang-yu Liu

Issue&Volume: January 10, 2022

Abstract: Organizational chirality on surfaces has been of interest in chemistry and materials science due to its scientific importance as well as its potential applications. Current methods for producing organizational chiral structures on surfaces are primarily based upon the self-assembly of molecules. While powerful, the chiral structures are restricted to those dictated by surface reaction thermodynamics. This work introduces a method to create organizational chirality by design with nanometer precision. Using atomic force microscopy-based nanolithography, in conjunction with chosen surface chemistry, various chiral structures are produced with nanometer precision, from simple spirals and arrays of nanofeatures to complex and hierarchical chiral structures. The size, geometry, and organizational chirality is achieved in deterministic fashion, with high fidelity to the designs. The concept and methodology reported here provide researchers a new and generic means to carry out organizational chiral chemistry, with the intrinsic advantages of chiral structures by design. The results open new and promising applications including enantioselective catalysis, separation, and crystallization, as well as optical devices requiring specific polarized radiation and fabrication and recognition of chiral nanomaterials.

DOI: 10.1021/jacs.1c10491

Source: https://pubs.acs.org/doi/10.1021/jacs.1c10491