美国加州大学Paula L. Diaconescu团队报道了电化学控制开环聚合制备ABC和ABAB嵌段共聚物。相关研究成果发表在2021年11月18日出版的《美国化学会杂志》。

该文报道了通过改变（salfan）Zr(OtBu)2（salfan=1,1′-二（2-叔丁基-6-N-甲基亚甲基苯氧基）二茂铁）的氧化还原状态，电化学控制合成多嵌段共聚物。借助于玻碳工作电极的电化学，原位电位开关在一锅中改变催化剂的氧化状态及其随后的单体（l-丙交酯、β-丁内酯或氧化环己烯）选择性。

研究人员制备了多种多嵌段共聚物，包括ABAB四嵌段共聚物聚（环己烯氧化物-b-丙交酯-b-环己烯氧化物-b-丙交酯）和ABC三嵌段共聚物聚（羟基丁酸酯-b-环己烯氧化物-b-丙交酯）。使用该技术生产的聚合物与通过化学氧化还原试剂法生产的聚合物相似，显示出适度窄的分散度（1.1–1.5），分子量范围为7到26 kDa不等。

附：英文原文

Title: ABC and ABAB Block Copolymers by Electrochemically Controlled Ring-Opening Polymerization

Author: Zachary C. Hern, Stephanie M. Quan, Ruxi Dai, Amy Lai, Yihang Wang, Chong Liu, Paula L. Diaconescu

Issue&Volume: November 18, 2021

Abstract: An electrochemically controlled synthesis of multiblock copolymers by alternating the redox states of (salfan)Zr(OtBu)2 (salfan = 1,1′-di(2-tert-butyl-6-N-methylmethylenephenoxy)ferrocene) is reported. Aided by electrochemistry with a glassy carbon working electrode, an in situ potential switch alters the catalyst’s oxidation state and its subsequent monomer (l-lactide, β-butyrolactone, or cyclohexene oxide) selectivity in one pot. Various multiblock copolymers were prepared, including an ABAB tetrablock copolymer, poly(cyclohexene oxide-b-lactide-b-cyclohexene oxide-b-lactide), and an ABC triblock copolymer, poly(hydroxybutyrate-b-cyclohexene oxide-b-lactide). The polymers produced using this technique are similar to those produced via a chemical redox reagent method, displaying moderately narrow dispersities (1.1–1.5) and molecular weights ranging from 7 to 26 kDa.

DOI: 10.1021/jacs.1c08648

Source: https://pubs.acs.org/doi/10.1021/jacs.1c08648