英国谢菲尔德大学Patrik Nosil小组在最新研究中揭示了隐性着色基因复合体进化中的大规模突变。相关论文于2020年7月24日发表于《科学》。

Title: Large-scale mutation in the evolution of a gene complex for cryptic coloration

Author: Romain Villoutreix, Clarissa F. de Carvalho, Víctor Soria-Carrasco, Dorothea Lindtke, Marisol De-la-Mora, Moritz Muschick, Jeffrey L. Feder, Thomas L. Parchman, Zach Gompert, Patrik Nosil

Issue&Volume: 2020/07/24

Abstract: The types of mutations affecting adaptation in the wild are only beginning to be understood. In particular, whether structural changes shape adaptation by suppressing recombination or by creating new mutations is unresolved. Here, we show that multiple linked but recombining loci underlie cryptic color morphs of Timema chumash stick insects. In a related species, these loci are found in a region of suppressed recombination, forming a supergene. However, in seven species of Timema, we found that a megabase-size “supermutation” has deleted color loci in green morphs. Moreover, we found that balancing selection likely contributes more to maintaining this mutation than does introgression. Our results show how suppressed recombination and large-scale mutation can help to package gene complexes into discrete units of diversity such as morphs, ecotypes, or species.

DOI: 10.1126/science.aaz4351

Source: https://science.sciencemag.org/content/369/6502/460