近日，美国华盛顿大学Jared M. Baeten等研究人员总结了暴露前预防（PrEP）在非洲的现状与机遇。该论文于2020年5月11日在线发表在《自然—医学》上。

研究人员表示，根据世界卫生组织在2015年提出的建议以及关键的临床试验，人类免疫缺陷病毒（HIV）负担最重的撒哈拉以南非洲地区国家制定了将PrEP纳入国家HIV预防政策中。到2019年底，全球接受PrEP的人中有三分之一以上在非洲。

研究人员认为，在高风险人群中早期推广PrEP至关重要，例如夫妻、青春期的女孩和年轻女性、女性性工作者以及与男性发生性关系的男性。让PrEP更易于获取、简化和高效的策略也同样重要。研究人员讨论了这些工作的当前状态以及如何进一步扩大其实施范围。

附：英文原文

Title: PrEP rollout in Africa: status and opportunity

Author: Elizabeth M. Irungu, Jared M. Baeten

Issue&Volume: 2020-05-11

Abstract: Following recommendations by the World Health Organization in 2015, and key clinical trials, countries in sub-Saharan Africa, the region with the highest burden of human immunodeficiency virus (HIV), developed policies that incorporate pre-exposure prophylaxis (PrEP) into national HIV-prevention strategies. By the end of 2019, more than one third of people receiving PrEP globally were in Africa. Crucial understandings gained from early rollout among at-risk populations, such as HIV-serodiscordant couples, adolescent girls and young women, female sex workers, and men who have sex with men, include the importance of strategies for maintaining persistent adherence to PrEP and novel approaches to making PrEP services accessible, simplified and efficient. This Perspective will discuss the current status of these programs and how to further widen their implementation.

DOI: 10.1038/s41591-020-0872-x

Source: https://www.nature.com/articles/s41591-020-0872-x