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研究揭示被子植物淹涝基因响应外部环境
作者:小柯机器人 发布时间:2019/9/20 12:39:31

美国加州大学Julia Bailey-Serres、埃默里大学Roger B. Deal、加州大学Siobhan M. Brady和Neelima Sinha课题组合作研究发现,被子植物可以在洪涝时灵活地响应线性进化。相关论文于2019年9月20日发表在《科学》上。

极端天气造成的洪水威胁着作物和生态系统,为了解被淹涝激活的基因调控网络的多样性,研究人员对四个被子植物的转录本控制的三个尺度上进行了高分辨率的染色质可及性和基因表达分析,从干旱适应的野生物种到湿地作物。 该数据定义了一组保守的淹涝激活基因,其具有由四个转录因子家族重叠顺式调控的特征。 同线基因比非同线基因表达更高,但两者都具有与淹涝上调相关的顺式基序和染色质可及性。尽管双子叶-单子叶植物可以根据其线性进行灵活的划分,但特定顺式基序的频率,染色质可及性的程度和淹涝激活程度在湿地作物中更普遍并且可能更容易适应环境。

附:英文原文

Title: Evolutionary flexibility in flooding response circuitry in angiosperms

Author: Mauricio A. Reynoso, Kaisa Kajala, Marko Bajic, Donnelly A. West, Germain Pauluzzi, Andrew I. Yao, Kathryn Hatch, Kristina Zumstein, Margaret Woodhouse, Joel Rodriguez-Medina, Neelima Sinha, Siobhan M. Brady, Roger B. Deal, Julia Bailey-Serres

Issue&Volume: Volume 365 Issue 6459

Abstract: 

Flooding due to extreme weather threatens crops and ecosystems. To understand variation in gene regulatory networks activated by submergence, we conducted a high-resolution analysis of chromatin accessibility and gene expression at three scales of transcript control in four angiosperms, ranging from a dryland-adapted wild species to a wetland crop. The data define a cohort of conserved submergence-activated genes with signatures of overlapping cis regulation by four transcription factor families. Syntenic genes are more highly expressed than nonsyntenic genes, yet both can have the cis motifs and chromatin accessibility associated with submergence up-regulation. Whereas the flexible circuitry spans the eudicot-monocot divide, the frequency of specific cis motifs, extent of chromatin accessibility, and degree of submergence activation are more prevalent in the wetland crop and may have adaptive importance.

DOI: 10.1126/science.aax8862

Source:https://science.sciencemag.org/content/365/6459/1291

期刊信息
Science:《科学》,创刊于1880年。隶属于美国科学促进会,最新IF:41.037