直播时间：2025年3月14日（周五）20:00-21:30

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【直播简介】

北京时间2025年3月14日晚八点，iCANX Talks 第218期邀请到了杜克大学Tony Jun Huang教授作为主讲嘉宾，北京大学教授Haixia Zhang、上海科技大学助理教授Xuejun Qian、中南大学教授Zeyu Chen担任研讨嘉宾，加州大学洛杉矶分校教授Paul Weiss和北京大学助理教授Hongjie Hu担任主持人。

这将是一场汇聚顶尖学者的盛会，共同探讨前沿科技与学术挑战！更多精彩，敬请期待！

【嘉宾介绍】

Tony Jun Huang

杜克大学

Acoustofluidics: Harnessing Acoustics and Fluid Mechanics for Biomedical Innovations

【Abstract】

The use of acoustics in medicine dates back to 350 BC when Hippocrates, known as the Father of Medicine, pioneered acoustic diagnostics, laying the groundwork for modern innovations. Today, acoustofluidics—the fusion of acoustics and fluid mechanics—is transforming biomedical research and clinical applications with unparalleled precision, versatility, and biocompatibility. It enables label-free, high-purity, high-yield isolation of critical biomarkers—including circulating tumor cells, extracellular vesicles, viruses, and proteins—from biofluids like blood, urine, and saliva, vastly outperforming traditional methods. Acoustofluidic devices facilitate non-invasive, high-throughput manipulation of bioparticles across eight orders of magnitude (from nanometers to centimeters) in virtually any medium, regardless of size, shape, or physical properties. Their scalability and adaptability drive advancements in diagnostics, therapeutics, and biomedical engineering, enabling next-generation apheresis, gene editing, and on-chip diagnostic tools for cancer, neurodegenerative, and infectious diseases. With their unmatched biocompatibility, precision, and efficiency, acoustofluidic technologies are revolutionizing medicine, bridging scientific innovation with clinical impact, and extending a legacy of sound-based medical breakthroughs that began over two millennia ago.

医学中声学的应用可以追溯到公元前350年，当时被称为“医学之父”的希波克拉底开创了声学诊断，为现代创新奠定了基础。如今，声流体学（声学与流体力学的结合）正以无与伦比的精确性、多功能性和生物相容性，彻底改变生物医学研究和临床应用。它可以实现从生物液体（如血液、尿液和唾液）中无标记、高纯度、高产量地分离关键生物标志物，包括循环肿瘤细胞、细胞外囊泡、病毒和蛋白质，远远优于传统方法。声流体装置能够在几乎所有介质中对生物颗粒进行非侵入式、高通量的操作，覆盖从纳米到厘米的八个数量级，无论其大小、形状或物理性质如何。其可扩展性和适应性推动了诊断、治疗和生物医学工程的进步，实现了下一代血液分离术、基因编辑以及用于癌症、神经退行性疾病和传染病的芯片诊断工具。凭借无与伦比的生物相容性、精确性和效率，声流体技术正在革新医学，将科学创新与临床影响相结合，延续了两千多年前开始的基于声学的医学突破传统。

【BIOGRAPHY】

Tony Jun Huang is the William Bevan Distinguished Professor of Mechanical Engineering and Materials Science at Duke University. Previously, he was a professor and the Huck Distinguished Chair in Bioengineering Science and Mechanics at The Pennsylvania State University. He received his Ph.D. in Mechanical and Aerospace Engineering from the University of California, Los Angeles (UCLA) in 2005. His research focuses on acoustofluidics, optofluidics, and micro/nano systems for biomedical diagnostics and therapeutics. He has authored or co-authored over 300 peer-reviewed journal articles, which have been cited more than 36,000 times, as documented by Google Scholar (h-index: 101), and holds 26 issued or pending patents. Prof. Huang is a fellow of the National Academy of Inventors (USA) and the European Academy of Sciences and Arts, as well as six professional societies: the American Association for the Advancement of Science (AAAS), the American Institute for Medical and Biological Engineering (AIMBE), the American Society of Mechanical Engineers (ASME), the Institute of Electrical and Electronics Engineers (IEEE), the Institute of Physics (UK), and the Royal Society of Chemistry (UK). His contributions have earned him prestigious awards, including the NIH Director’s New Innovator Award (2010), the Outstanding Young Manufacturing Engineer Award from the Society for Manufacturing Engineering (2012), the IEEE Sensors Council Technical Achievement Award (2014), the Analytical Chemistry Young Innovator Award from the American Chemical Society (2017), the Van Mow Medal from ASME (2019), and the Technical Achievement Award from the IEEE Engineering in Medicine and Biology Society (2019). In the last two consecutive years (2022-2023), he has been named to a global list of the most highly cited researchers (cross field) by Clarivate (Web of Science).

黄俊（Tony Jun Huang）是杜克大学机械工程与材料科学系威廉·贝文杰出教授。此前，他曾是宾夕法尼亚州立大学生物工程科学与力学系教授及赫克杰出讲席教授。他于2005年在加利福尼亚大学洛杉矶分校（UCLA）获得机械与航空航天工程博士学位。他的研究专注于声流体学、光流体学以及用于生物医学诊断和治疗的微纳系统。他发表或共同发表的300多篇同行评审期刊文章被引用超过36,000次，谷歌学术记录显示其h指数为101，他还持有26项已授权或待审批的专利。黄教授是美国国家发明家学院和欧洲科学与艺术学院的院士，同时也是六个专业学会的会士：美国科学促进会（AAAS）、美国医学与生物工程学会（AIMBE）、美国机械工程师学会（ASME）、电气与电子工程师学会（IEEE）、英国物理学会和英国皇家化学学会。他的贡献为他赢得了诸多荣誉，包括美国国立卫生研究院主任新创新者奖（2010年）、制造工程师学会杰出青年制造工程师奖（2012年）、IEEE传感器委员会技术成就奖（2014年）、美国化学会分析化学青年创新奖（2017年）、ASME范·莫奖（2019年）以及IEEE生物医学工程学会技术成就奖（2019年）。在最近连续两年（2022-2023年），他被Clarivate（Web of Science）评为全球引用次数最高的跨领域研究人员之一。