韩国首尔大学Dongwhan Lee团队在水中制备蜡盐，通过阴离子诱导疏水性的综合控制导致聚集增强发光。 相关研究成果于2021年2月21日发表于国际一流学术期刊《德国应用化学》。

研究人员发现多极性阳离子受体在水中起到了阴离子响应型光发射体的作用。流行的范式是利用刚性的孔洞和空穴来识别离子。相反，研究人员构建了开放的两亲性支架，在阴离子络合作用下，引发阳离子荧光团周围极性到非极性环境的转变。高氯酸盐作为非球形疏水阴离子模型证明了这种离子配对和聚集事件会导致发射强度的显著增强。C–H···阴离子氢键和紧密的阴离子-π+接触的协同作用支撑了这种超分子现象。

通过改变脂肪族链的长度，研究人员证明了这个信号事件的响应曲线和阈值可以在分子水平上控制。通过适当的分子设计，固有的弱的、不明确的、无方向性的范德华相互作用能够在水中实现选择性的、灵敏的和可调的识别。

附：英文原文

Title: Making Waxy Salts in Water: Synthetic Control of Hydrophobicity for Anion‐Induced and Aggregation‐Enhanced Light Emission

Author: Soohyung Kim, Jongmin Kim, Dongwhan Lee

Issue&Volume: 2021-02-21

Abstract: We show that multipodal polycationic receptors function as anion‐responsive light‐emitters in water. Prevailing paradigms utilize rigid holes and cavities for ion recognition. We instead built open amphiphilic scaffolds that trigger polar‐to‐nonpolar environment transitions around cationic fluorophores upon anion complexation. This ion‐pairing and aggregation event produces a dramatic enhancement in the emission intensity, as demonstrated by perchlorate as a non‐spherical hydrophobic anion model. A synergetic interplay of C–H···anion hydrogen bonding and tight anion–π  +  contacts underpins this supramolecular phenomenon. By changing the aliphatic chain length, we demonstrate that the response profile and threshold of this signaling event can be controlled at the molecular level. With appropriate molecular design, inherently weak, ill‐defined, and non‐directional van der Waals interaction enables selective, sensitive, and tunable recognition in water.

DOI: 10.1002/anie.202100729

Source: https://onlinelibrary.wiley.com/doi/10.1002/anie.202100729