为了确定从1999-2000年至2017-2018年美国成人高血压患者的血压控制情况是否发生变化，研究组采用全国健康和营养检查的数据，对18262名18岁以上的高血压成人在1999-2000至2017-2018年间（10个周期）进行分析，高血压定义为收缩压高于140 mmHg，舒张压高于90 mmHg，或使用抗高血压药物治疗。血压控制定义为收缩压低于140 mmHg，舒张压低于90 mmHg。
Title: Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018
Author: Paul Muntner, Shakia T. Hardy, Lawrence J. Fine, Byron C. Jaeger, Gregory Wozniak, Emily B. Levitan, Lisandro D. Colantonio
Importance Controlling blood pressure (BP) reduces the risk for cardiovascular disease.
Objective To determine whether BP control among US adults with hypertension changed from 1999-2000 through 2017-2018.
Design, Setting, and Participants Serial cross-sectional analysis of National Health and Nutrition Examination Survey data, weighted to be representative of US adults, between 1999-2000 and 2017-2018 (10 cycles), including 18262 US adults aged 18 years or older with hypertension defined as systolic BP level of 140 mm Hg or higher, diastolic BP level of 90 mm Hg or higher, or use of antihypertensive medication. The date of final data collection was 2018.
Exposures Calendar year.
Main Outcomes and Measures Mean BP was computed using 3 measurements. The primary outcome of BP control was defined as systolic BP level lower than 140 mm Hg and diastolic BP level lower than 90 mm Hg.
Results Among the 51761 participants included in this analysis, the mean (SD) age was 48 (19) years and 25939 (50.1%) were women; 43.2% were non-Hispanic White adults; 21.6%, non-Hispanic Black adults; 5.3%, non-Hispanic Asian adults; and 26.1%, Hispanic adults. Among the 18262 adults with hypertension, the age-adjusted estimated proportion with controlled BP increased from 31.8% (95% CI, 26.9%-36.7%) in 1999-2000 to 48.5% (95% CI, 45.5%-51.5%) in 2007-2008 (P<.001 for trend), remained stable and was 53.8% (95% CI, 48.7%-59.0%) in 2013-2014 (P=.14 for trend), and then declined to 43.7% (95% CI, 40.2%-47.2%) in 2017-2018 (P=.003 for trend). Compared with adults who were aged 18 years to 44 years, it was estimated that controlled BP was more likely among those aged 45 years to 64 years (49.7% vs 36.7%; multivariable-adjusted prevalence ratio, 1.18 [95% CI, 1.02-1.37]) and less likely among those aged 75 years or older (37.3% vs 36.7%; multivariable-adjusted prevalence ratio, 0.81 [95% CI, 0.65-0.97]). It was estimated that controlled BP was less likely among non-Hispanic Black adults vs non-Hispanic White adults (41.5% vs 48.2%, respectively; multivariable-adjusted prevalence ratio, 0.88; 95% CI, 0.81-0.96). Controlled BP was more likely among those with private insurance (48.2%), Medicare (53.4%), or government health insurance other than Medicare or Medicaid (43.2%) vs among those without health insurance (24.2%) (multivariable-adjusted prevalence ratio, 1.40 [95% CI, 1.08-1.80], 1.47 [95% CI, 1.15-1.89], and 1.36 [95% CI, 1.04-1.76], respectively). Controlled BP was more likely among those with vs those without a usual health care facility (48.4% vs 26.5%, respectively; multivariable-adjusted prevalence ratio, 1.48 [95% CI, 1.13-1.94]) and among those who had vs those who had not had a health care visit in the past year (49.1% vs 8.0%; multivariable-adjusted prevalence ratio, 5.23 [95% CI, 2.88-9.49]).
Conclusions and Relevance In a series of cross-sectional surveys weighted to be representative of the adult US population, the prevalence of controlled BP increased between 1999-2000 and 2007-2008, did not significantly change from 2007-2008 through 2013-2014, and then decreased after 2013-2014.