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科学家总结COVID-19对神经系统的影响
作者:小柯机器人 发布时间:2020/8/21 16:00:00

近日,美国康奈尔大学Costantino Iadecola等研究人员总结了COVID-19对神经系统的影响。2020年8月19日,《细胞》杂志在线发表了这一论文。

研究人员表示,当前的COVID-19大流行中,神经系统并发症已成为发病率和死亡率的重要原因。除了呼吸功能不全之外,许多住院患者还表现出神经系统表现,从头痛和气味消失到精神错乱和中风。从长远来看,COVID-19也有可能对神经系统造成损害。
 
研究人员将对SARS-CoV-2的嗜神经性和神经发病机制进行了重要评估,因为它们与感染的急性和慢性神经系统后果有关。最后,研究人员将评估未来研究和治疗开发的潜在途径。
 
附:英文原文

Title: Effects of COVID-19 on the nervous system

Author: Costantino Iadecola, Josef Anrather, Hooman Kamel

Issue&Volume:

Abstract: Neurological complications have emerged as a significant cause of morbidity and mortality in the ongoing COVID-19 pandemic. Beside respiratory insufficiency, many hospitalized patients exhibit neurological manifestations, ranging from headache and loss of smell, to confusion and disabling strokes. COVID-19 is also anticipated to take a toll on the nervous system in the long term. Here we will provide a critical appraisal of the potential for neurotropism and mechanisms of neuropathogenesis of SARS-CoV-2, as they relate to the acute and chronic neurological consequences of the infection. Finally, we will examine potential avenues for future research and therapeutic development.

DOI: 10.1016/j.cell.2020.08.028

Source: https://www.cell.com/cell/fulltext/S0092-8674(20)31070-9

 

期刊信息
Cell:《细胞》,创刊于1974年。隶属于细胞出版社,最新IF:36.216
官方网址:https://www.cell.com/