近日,美国康奈尔大学Costantino Iadecola等研究人员总结了COVID-19对神经系统的影响。2020年8月19日,
Title: Effects of COVID-19 on the nervous system
Author: Costantino Iadecola, Josef Anrather, Hooman Kamel
Issue&Volume:
Abstract: Neurological complications have emerged as a significant cause of morbidity and mortality in the ongoing COVID-19 pandemic. Beside respiratory insufficiency, many hospitalized patients exhibit neurological manifestations, ranging from headache and loss of smell, to confusion and disabling strokes. COVID-19 is also anticipated to take a toll on the nervous system in the long term. Here we will provide a critical appraisal of the potential for neurotropism and mechanisms of neuropathogenesis of SARS-CoV-2, as they relate to the acute and chronic neurological consequences of the infection. Finally, we will examine potential avenues for future research and therapeutic development.
DOI: 10.1016/j.cell.2020.08.028
Source: https://www.cell.com/cell/fulltext/S0092-8674(20)31070-9