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现实网络建模揭示最为有效的COVID-19控制策略
作者:小柯机器人 发布时间:2020/8/11 18:16:31

英国东英吉利大学Lewis G. Spurgin等研究人员建模分析了最为有效的COVID-19控制策略。相关论文于2020年8月7日在线发表在《自然—医学》杂志上。

研究人员表示,病例隔离和接触者追踪可有助于控制COVID-19疫情。但是,目前尚不清楚现实世界中的社交网络如何影响这种方法的有效性和效率。
 
为了解决这个问题,研究人员在现实世界的社交网络中模拟了SARS-CoV-2传播的控制策略,该社交网络是通过在公民科学实验过程中收集的高分辨率GPS数据生成的。研究人员发现,追踪接触者的接触者比仅追踪接触者减少了模拟爆发的规模,但是这种策略还导致几乎一半的本地人口在同一时间被隔离。对非传染性个体进行检疫和隔离检疫导致爆发规模增加,这表明当接触率很高时,接触者追踪和检疫可能是最有效的“本地封锁”策略。
 
最后,研究人员估计将物理间隔与接触者跟踪相结合可以实现流行病控制,同时减少被隔离人员的数量。这些研究结果表明,与其他控制措施(例如物理间隔)结合使用时,目标跟踪和隔离策略将是最有效的。
 
附:英文原文

Title: Using a real-world network to model localized COVID-19 control strategies

Author: Josh A. Firth, Joel Hellewell, Petra Klepac, Stephen Kissler, Adam J. Kucharski, Lewis G. Spurgin

Issue&Volume: 2020-08-07

Abstract: Case isolation and contact tracing can contribute to the control of COVID-19 outbreaks1,2. However, it remains unclear how real-world social networks could influence the effectiveness and efficiency of such approaches. To address this issue, we simulated control strategies for SARS-CoV-2 transmission in a real-world social network generated from high-resolution GPS data that were gathered in the course of a citizen-science experiment3,4. We found that tracing the contacts of contacts reduced the size of simulated outbreaks more than tracing of only contacts, but this strategy also resulted in almost half of the local population being quarantined at a single point in time. Testing and releasing non-infectious individuals from quarantine led to increases in outbreak size, suggesting that contact tracing and quarantine might be most effective as a ‘local lockdown’ strategy when contact rates are high. Finally, we estimated that combining physical distancing with contact tracing could enable epidemic control while reducing the number of quarantined individuals. Our findings suggest that targeted tracing and quarantine strategies would be most efficient when combined with other control measures such as physical distancing.

DOI: 10.1038/s41591-020-1036-8

Source: https://www.nature.com/articles/s41591-020-1036-8

期刊信息

Nature Medicine:《自然—医学》,创刊于1995年。隶属于施普林格·自然出版集团,最新IF:30.641
官方网址:https://www.nature.com/nm/
投稿链接:https://mts-nmed.nature.com/cgi-bin/main.plex