以色列特拉维夫大学Yossi Yovel、Yaniv Assaf课题组，揭示了哺乳动物间大脑连接和布线的保守性。该研究成果于2020年6月8日发表在《自然—神经科学》上。

一百多年前，Ramon y Cajal提出了两种作用力在哺乳动物大脑连接进化中的作用：最小化布线成本和最大化电导速率。 在最新论文中，研究人员使用扩散核磁共振成像，研究人员重建了123个哺乳动物的大脑连接组。

网络分析表明，哺乳动物之间的连接性和布线成本均得到了保留。研究人员揭示了一种保持总体连通性的保守原则：半球间连接较少的物种表现出更好的半球内连通性。

附：英文原文

Title: Conservation of brain connectivity and wiring across the mammalian class

Author: Yaniv Assaf, Arieli Bouznach, Omri Zomet, Assaf Marom, Yossi Yovel

Issue&Volume: 2020-06-08

Abstract: Over 100 years ago, Ramon y Cajal hypothesized that two forces played a role in the evolution of mammalian brain connectivity: minimizing wiring costs and maximizing conductivity speed. Using diffusion MRI, we reconstructed the brain connectomes of 123 mammalian species. Network analysis revealed that both connectivity and the wiring cost are conserved across mammals. We describe a conservation principle that maintains the overall connectivity: species with fewer interhemispheric connections exhibit better intrahemispheric connectivity.

DOI: 10.1038/s41593-020-0641-7

Source: https://www.nature.com/articles/s41593-020-0641-7