美国西奈山伊坎医学院Harm van Bakel、Viviana Simon、Emilia Mia Sordillo等研究人员，合作揭示了纽约市区新冠病毒（SARS-CoV-2）早期传播的轨迹。该研究于2020年5月29日在线发表于《科学》。

Title: Introductions and early spread of SARS-CoV-2 in the New York City area

Author: Ana S. Gonzalez-Reiche, Matthew M. Hernandez, Mitchell J. Sullivan, Brianne Ciferri, Hala Alshammary, Ajay Obla, Shelcie Fabre, Giulio Kleiner, Jose Polanco, Zenab Khan, Bremy Alburquerque, Adriana van de Guchte, Jayeeta Dutta, Nancy Francoeur, Betsaida Salom Melo, Irina Oussenko, Gintaras Deikus, Juan Soto, Shwetha Hara Sridhar, Ying-Chih Wang, Kathryn Twyman, Andrew Kasarskis, Deena R. Altman, Melissa Smith, Robert Sebra, Judith Aberg, Florian Krammer, Adolfo García-Sastre, Marta Luksza, Gopi Patel, Alberto Paniz-Mondolfi, Melissa Gitman, Emilia Mia Sordillo, Viviana Simon, Harm van Bakel

Issue&Volume: 2020/05/29

Abstract: Abstract New York City (NYC) has emerged as one of the epicenters of the current SARS-CoV-2 pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus causing COVID-19 in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV2 genomes indicates multiple, independent but isolated introductions mainly from Europe and other parts of the United States. Moreover, we find evidence for community transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city.

DOI: 10.1126/science.abc1917

Source: https://science.sciencemag.org/content/early/2020/05/28/science.abc1917